The journey from features to compound ID in metabolomics

Metabolomics is at the bottom of the -omics cascade, after genomics, transcriptomics, and proteomics. If a particular metabolite is changing, it is indicative of a certain pathway being altered. With DNA, RNA, and proteins that’s not always the case; for example, a gene or protein might be present or not, but neither scenario has a direct consequence on the phenotype.