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Press Releases

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  • Living off the fat of the land

    Living off the fat of the land Cancer cells are defined by their ability for uncontrolled growth, one cell quickly becoming two becoming many. “It’s a fascinating process,” said Gary Patti, associate professor of chemistry in Arts & Sciences at Washington University in St. Louis. “Imagine creating two copies of yourself every few days, instead…
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  • Increasing probability for discovery

    Increasing probability for discovery Every Friday evening, you stop at the corner ­convenience store on your way home from work and purchase your weekly allotment of lottery tickets, one, for the Saturday evening drawing. You figure, why not? Even though your chances are around 1 in 292 million, your investment is low and you still have…
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  • Metabolomics study reveals another energy source for cancer cells

    Metabolomics study reveals another energy source for cancer cells Researchers have discovered another way that cancer cells may produce the energy they need to survive and grow. Using new metabolomics technologies, the researchers found that cancer cells can use the compound lactate to fuel biochemical reactions and to generate other compounds needed for cell growth,…
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  • Liposuction: Extracellular Fat Removal Promotes Proliferation

    Liposuction: Extracellular Fat Removal Promotes Proliferation The construction of daughter cells requires duplicating the macromolecular biomass of the parent. Anabolic metabolism converts raw carbohydrate and amino acid material into protein, nucleic acid, and lipid building blocks required for new cells. In particular, the membranes that surround cells and organelles require significant amounts of fatty acid…
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  • Tracking bugs reveal secret of cancer cell metabolism

    ‘Tracking bugs’ reveal secret of cancer cell metabolism One of the hallmarks of cancer is a change in cellular metabolism, a series of chemical reactions so fundamental to life that their alteration makes cancer cells seem creepily malevolent.
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  • How to target tumours by messing with their metabolism

    How to target tumours by messing with their metabolism IN 1924, German biochemist Otto Warburg observed that cancer cells are extraordinarily greedy. Tumours tend to grow rapidly, so it made sense that they had outsized appetites. But Warburg also found that the way they burned, or metabolised, the resources they gobbled so hungrily was different. He…
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  • Patti receives Agilent Early Career Professor Award

    Patti receives Agilent Early Career Professor Award Gary J. Patti, associate professor of chemistry in Arts & Sciences at Washington University in St. Louis, has received a 2017 Agilent Early Career Professor Award. The honor includes a $100,000 research award and is given to those who have made “significant original research contributions” and have “outstanding…
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  • Metabolomics just got smaller

    Metabolomics just got smaller Not long ago, scientists placed wagers on the number of genes in the human genome. Some bets ranged upward of 100,000 genes being present. Once the human genome sequence was completed, a project led in part by the McDonnell Genome Institute at Washington University School of Medicine in St. Louis, even…
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  • Patti rolling on RIVER grant

    Patti rolling on RIVER grant The National Institutes of Health (NIH) has awarded an eight-year, $5.85 million grant to Gary Patti, associate professor of chemistry in Arts & Sciences at Washington University in St. Louis, for research.
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  • Metabolomics data under scrutiny

    Metabolomics data under scrutiny Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.
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